G435-1100 Screening compound: N-[(3-chloro-4-fluorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

G435-1100 Screening compound: N-[(3-chloro-4-fluorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide
G435-1100 Screening compound: N-[(3-chloro-4-fluorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-1100
N-[(3-chloro-4-fluorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-1100

Molecular Formula

C25H22ClF2N5O (C25 H22 ClF2 N5 O)

Compound Name

N-[(3-chloro-4-fluorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

IUPAC name

N-[(3-chloro-4-fluorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[15-a]pyrazin-4-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(c1c2)nccn1nc2-c(cc1)ccc1F)NCc(cc1)cc(Cl)c1F

InChI

InChI=1S/C25H22ClF2N5O/c26-20-13-16(1-6-21(20)28)15-30-25(34)18-7-10-32(11-8-18)24-23-14-22(31-33(23)12-9-29-24)17-2-4-19(27)5-3-17/h1-6,9,12-14,18H,7-8,10-11,15H2,(H,30,34)

InChI Key

QVFRYRCVJOMHNY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142223

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.93

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.390

Distribution Coefficient, logD

4.388

Water Solubility, LogSw

-4.52

Polar Surface Area

47.688

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

G435-1100 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system

References: we are preparing a list of scientific research reports with G435-1100 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-1100?
Check Price and Availability of G435-1100, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G435-1100 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-1100
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-1100
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-1100 available by request