G435-1128 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

G435-1128 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide
G435-1128 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-1128
1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-1128

Molecular Formula

C26H28N6O (C26 H28 N6 O)

Compound Name

1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-[2-(34-dimethylphenyl)pyrazolo[15-a]pyrazin-4-yl]-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

SMILES

Cc(cc1)c(C)cc1-c1nn(ccnc2N(CC3)CCC3C(NCc3ccncc3)=O)c2c1

InChI

InChI=1S/C26H28N6O/c1-18-3-4-22(15-19(18)2)23-16-24-25(28-11-14-32(24)30-23)31-12-7-21(8-13-31)26(33)29-17-20-5-9-27-10-6-20/h3-6,9-11,14-16,21H,7-8,12-13,17H2,1-2H3,(H,29,33)

InChI Key

DPUNGEKMHDELNP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142240

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.252

Distribution Coefficient, logD

3.248

Water Solubility, LogSw

-2.99

Polar Surface Area

57.116

Acid Dissociation Constant (pKa)

13.00

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

G435-1128 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G435-1128 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-1128?
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What is the minimum amount of G435-1128 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-1128
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-1128
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-1128 available by request