G435-1133 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

G435-1133 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide
G435-1133 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-1133
1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-1133

Molecular Formula

C28H31N5OS (C28 H31 N5 OS)

Compound Name

1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

IUPAC name

1-[2-(34-dimethylphenyl)pyrazolo[15-a]pyrazin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-4-carboxamide

SMILES

Cc(cc1)c(C)cc1-c1nn(ccnc2N(CC3)CCC3C(NCc(cc3)ccc3SC)=O)c2c1

InChI

InChI=1S/C28H31N5OS/c1-19-4-7-23(16-20(19)2)25-17-26-27(29-12-15-33(26)31-25)32-13-10-22(11-14-32)28(34)30-18-21-5-8-24(35-3)9-6-21/h4-9,12,15-17,22H,10-11,13-14,18H2,1-3H3,(H,30,34)

InChI Key

AHFZUNMCFAMWBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142245

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.65

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.328

Distribution Coefficient, logD

5.325

Water Solubility, LogSw

-5.31

Polar Surface Area

47.688

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

5.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

G435-1133 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G435-1133 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-1133?
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What is the minimum amount of G435-1133 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-1133
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-1133
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-1133 available by request