G435-1258 Screening compound: N-[(2,4-difluorophenyl)methyl]-1-[2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

G435-1258 Screening compound: N-[(2,4-difluorophenyl)methyl]-1-[2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide
G435-1258 Screening compound: N-[(2,4-difluorophenyl)methyl]-1-[2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-1258
N-[(2,4-difluorophenyl)methyl]-1-[2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-1258

Molecular Formula

C26H25F2N5O2 (C26 H25 F2 N5 O2)

Compound Name

N-[(2,4-difluorophenyl)methyl]-1-[2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

IUPAC name

N-[(24-difluorophenyl)methyl]-1-[2-(3-methoxyphenyl)pyrazolo[15-a]pyrazin-4-yl]piperidine-4-carboxamide

SMILES

COc1cccc(-c2nn(ccnc3N(CC4)CCC4C(NCc(ccc(F)c4)c4F)=O)c3c2)c1

InChI

InChI=1S/C26H25F2N5O2/c1-35-21-4-2-3-18(13-21)23-15-24-25(29-9-12-33(24)31-23)32-10-7-17(8-11-32)26(34)30-16-19-5-6-20(27)14-22(19)28/h2-6,9,12-15,17H,7-8,10-11,16H2,1H3,(H,30,34)

InChI Key

PDQDPVFMIGEHDG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20740534

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.098

Distribution Coefficient, logD

4.091

Water Solubility, LogSw

-4.27

Polar Surface Area

55.232

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

G435-1258 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G435-1258 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-1258?
Check Price and Availability of G435-1258, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G435-1258 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-1258
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-1258
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-1258 available by request