G487-0083 Screening compound: 1-{2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

G487-0083 Screening compound: 1-{2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
G487-0083 Screening compound: 1-{2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound G487-0083
1-{2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G487-0083

Molecular Formula

C21H24N4O3 (C21 H24 N4 O3)

Compound Name

1-{2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

IUPAC name

1-{2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-46-dimethyl-2-oxo-12-dihydropyridine-3-carbonitrile

SMILES

CC(C=C(C)N(CC(N(CC1)CCN1c(cccc1)c1OC)=O)C1=O)=C1C#N

InChI

InChI=1S/C21H24N4O3/c1-15-12-16(2)25(21(27)17(15)13-22)14-20(26)24-10-8-23(9-11-24)18-6-4-5-7-19(18)28-3/h4-7,12H,8-11,14H2,1-3H3

InChI Key

GYVHBXILTDWJAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014245

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.679

Distribution Coefficient, logD

1.679

Water Solubility, LogSw

-1.99

Polar Surface Area

59.465

Acid Dissociation Constant (pKa)

25.73

Base Dissociation Constant (pKb)

4.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

G487-0083 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G487-0083 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G487-0083?
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What is the minimum amount of G487-0083 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G487-0083
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G487-0083
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G487-0083 available by request