G487-0332 Screening compound: 3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(2-methoxyphenyl)methyl]benzamide

G487-0332 Screening compound: 3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(2-methoxyphenyl)methyl]benzamide
G487-0332 Screening compound: 3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(2-methoxyphenyl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G487-0332
3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(2-methoxyphenyl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G487-0332

Molecular Formula

C25H24N4O4 (C25 H24 N4 O4)

Compound Name

3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(2-methoxyphenyl)methyl]benzamide

IUPAC name

3-[2-(3-cyano-46-dimethyl-2-oxo-12-dihydropyridin-1-yl)acetamido]-N-[(2-methoxyphenyl)methyl]benzamide

SMILES

CC(C=C(C)N(CC(Nc1cc(C(NCc(cccc2)c2OC)=O)ccc1)=O)C1=O)=C1C#N

InChI

InChI=1S/C25H24N4O4/c1-16-11-17(2)29(25(32)21(16)13-26)15-23(30)28-20-9-6-8-18(12-20)24(31)27-14-19-7-4-5-10-22(19)33-3/h4-12H,14-15H2,1-3H3,(H,27,31)(H,28,30)

InChI Key

DDJSVXDGKVYINT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014269

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.134

Distribution Coefficient, logD

3.134

Water Solubility, LogSw

-3.36

Polar Surface Area

87.676

Acid Dissociation Constant (pKa)

11.65

Base Dissociation Constant (pKb)

-1.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G487-0332 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G487-0332 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G487-0332?
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What is the minimum amount of G487-0332 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G487-0332
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G487-0332
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G487-0332 available by request