G487-0373 Screening compound: ethyl 4-{3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]benzamido}piperidine-1-carboxylate

G487-0373 Screening compound: ethyl 4-{3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]benzamido}piperidine-1-carboxylate
G487-0373 Screening compound: ethyl 4-{3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]benzamido}piperidine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G487-0373
ethyl 4-{3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]benzamido}piperidine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G487-0373

Molecular Formula

C25H29N5O5 (C25 H29 N5 O5)

Compound Name

ethyl 4-{3-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]benzamido}piperidine-1-carboxylate

IUPAC name

ethyl 4-{3-[2-(3-cyano-46-dimethyl-2-oxo-12-dihydropyridin-1-yl)acetamido]benzamido}piperidine-1-carboxylate

SMILES

CCOC(N(CC1)CCC1NC(c1cccc(NC(CN(C(C)=CC(C)=C2C#N)C2=O)=O)c1)=O)=O

InChI

InChI=1S/C25H29N5O5/c1-4-35-25(34)29-10-8-19(9-11-29)28-23(32)18-6-5-7-20(13-18)27-22(31)15-30-17(3)12-16(2)21(14-26)24(30)33/h5-7,12-13,19H,4,8-11,15H2,1-3H3,(H,27,31)(H,28,32)

InChI Key

ONMWCPSBERZKSF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014288

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.299

Distribution Coefficient, logD

2.299

Water Solubility, LogSw

-2.91

Polar Surface Area

102.551

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

3.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

G487-0373 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G487-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G487-0373?
Check Price and Availability of G487-0373, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G487-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G487-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G487-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G487-0373 available by request