G487-0476 Screening compound: 4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-(3-ethoxypropyl)benzamide

G487-0476 Screening compound: 4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-(3-ethoxypropyl)benzamide
G487-0476 Screening compound: 4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-(3-ethoxypropyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G487-0476
4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-(3-ethoxypropyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G487-0476

Molecular Formula

C22H26N4O4 (C22 H26 N4 O4)

Compound Name

4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-(3-ethoxypropyl)benzamide

IUPAC name

4-[2-(3-cyano-46-dimethyl-2-oxo-12-dihydropyridin-1-yl)acetamido]-N-(3-ethoxypropyl)benzamide

SMILES

CCOCCCNC(c(cc1)ccc1NC(CN(C(C)=CC(C)=C1C#N)C1=O)=O)=O

InChI

InChI=1S/C22H26N4O4/c1-4-30-11-5-10-24-21(28)17-6-8-18(9-7-17)25-20(27)14-26-16(3)12-15(2)19(13-23)22(26)29/h6-9,12H,4-5,10-11,14H2,1-3H3,(H,24,28)(H,25,27)

InChI Key

NUXPKAHXYZCMJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014352

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.608

Distribution Coefficient, logD

1.607

Water Solubility, LogSw

-2.23

Polar Surface Area

88.136

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G487-0476 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G487-0476 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G487-0476?
Check Price and Availability of G487-0476, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G487-0476 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G487-0476
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G487-0476
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G487-0476 available by request