G487-0491 Screening compound: 4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-{[2-(trifluoromethyl)phenyl]methyl}benzamide

G487-0491 Screening compound: 4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-{[2-(trifluoromethyl)phenyl]methyl}benzamide
G487-0491 Screening compound: 4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-{[2-(trifluoromethyl)phenyl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G487-0491
4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-{[2-(trifluoromethyl)phenyl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G487-0491

Molecular Formula

C25H21F3N4O3 (C25 H21 F3 N4 O3)

Compound Name

4-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-{[2-(trifluoromethyl)phenyl]methyl}benzamide

IUPAC name

4-[2-(3-cyano-46-dimethyl-2-oxo-12-dihydropyridin-1-yl)acetamido]-N-{[2-(trifluoromethyl)phenyl]methyl}benzamide

SMILES

CC(C=C(C)N(CC(Nc(cc1)ccc1C(NCc1c(C(F)(F)F)cccc1)=O)=O)C1=O)=C1C#N

InChI

InChI=1S/C25H21F3N4O3/c1-15-11-16(2)32(24(35)20(15)12-29)14-22(33)31-19-9-7-17(8-10-19)23(34)30-13-18-5-3-4-6-21(18)25(26,27)28/h3-11H,13-14H2,1-2H3,(H,30,34)(H,31,33)

InChI Key

STSQFFHFFMOIAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014359

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.662

Distribution Coefficient, logD

3.662

Water Solubility, LogSw

-3.89

Polar Surface Area

80.046

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

-1.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G487-0491 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G487-0491 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G487-0491?
Check Price and Availability of G487-0491, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G487-0491 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G487-0491
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G487-0491
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G487-0491 available by request