G487-0557 Screening compound: 2-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(4-ethylphenyl)methyl]benzamide

G487-0557 Screening compound: 2-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(4-ethylphenyl)methyl]benzamide
G487-0557 Screening compound: 2-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(4-ethylphenyl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G487-0557
2-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(4-ethylphenyl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G487-0557

Molecular Formula

C26H26N4O3 (C26 H26 N4 O3)

Compound Name

2-[2-(3-cyano-4,6-dimethyl-2-oxo-1,2-dihydropyridin-1-yl)acetamido]-N-[(4-ethylphenyl)methyl]benzamide

IUPAC name

2-[2-(3-cyano-46-dimethyl-2-oxo-12-dihydropyridin-1-yl)acetamido]-N-[(4-ethylphenyl)methyl]benzamide

SMILES

CCc1ccc(CNC(c(cccc2)c2NC(CN(C(C)=CC(C)=C2C#N)C2=O)=O)=O)cc1

InChI

InChI=1S/C26H26N4O3/c1-4-19-9-11-20(12-10-19)15-28-25(32)21-7-5-6-8-23(21)29-24(31)16-30-18(3)13-17(2)22(14-27)26(30)33/h5-13H,4,15-16H2,1-3H3,(H,28,32)(H,29,31)

InChI Key

ONHZHRSMTWETJC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014400

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.570

Distribution Coefficient, logD

3.570

Water Solubility, LogSw

-3.69

Polar Surface Area

79.348

Acid Dissociation Constant (pKa)

10.59

Base Dissociation Constant (pKb)

-1.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

G487-0557 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G487-0557 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G487-0557?
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What is the minimum amount of G487-0557 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G487-0557
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G487-0557
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G487-0557 available by request