G490-0428 Screening compound: 3-(4-METHOXYPHENYL)-8-[(4-METHOXYPHENYL)METHYL]-1,4,8-TRIAZASPIRO[4.5]DEC-3-EN-2-ONE

G490-0428 Screening compound: 3-(4-METHOXYPHENYL)-8-[(4-METHOXYPHENYL)METHYL]-1,4,8-TRIAZASPIRO[4.5]DEC-3-EN-2-ONE
G490-0428 Screening compound: 3-(4-METHOXYPHENYL)-8-[(4-METHOXYPHENYL)METHYL]-1,4,8-TRIAZASPIRO[4.5]DEC-3-EN-2-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound G490-0428
3-(4-METHOXYPHENYL)-8-[(4-METHOXYPHENYL)METHYL]-1,4,8-TRIAZASPIRO[4.5]DEC-3-EN-2-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G490-0428

Molecular Formula

C22H25N3O3 (C22 H25 N3 O3)

Compound Name

3-(4-METHOXYPHENYL)-8-[(4-METHOXYPHENYL)METHYL]-1,4,8-TRIAZASPIRO[4.5]DEC-3-EN-2-ONE

IUPAC name

n/a

SMILES

COc1ccc(CN(CC2)CCC2(NC2=O)N=C2c(cc2)ccc2OC)cc1

InChI

InChI=1S/C22H25N3O3/c1-27-18-7-3-16(4-8-18)15-25-13-11-22(12-14-25)23-20(21(26)24-22)17-5-9-19(28-2)10-6-17/h3-10H,11-15H2,1-2H3,(H,24,26)

InChI Key

OZSGBRZVYJKEOD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.662

Distribution Coefficient, logD

1.375

Water Solubility, LogSw

-3.00

Polar Surface Area

52.409

Acid Dissociation Constant (pKa)

9.36

Base Dissociation Constant (pKb)

8.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G490-0428 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G490-0428 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G490-0428?
Check Price and Availability of G490-0428, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G490-0428 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G490-0428
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G490-0428
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G490-0428 available by request