G497-0019 Screening compound: 4-bromo-N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-1-benzenesulfonamide

G497-0019 Screening compound: 4-bromo-N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-1-benzenesulfonamide
G497-0019 Screening compound: 4-bromo-N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G497-0019
4-bromo-N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G497-0019

Molecular Formula

C15H15BrN2O4S2 (C15 H15 BrN2 O4 S2)

Compound Name

4-bromo-N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-1-benzenesulfonamide

IUPAC name

4-bromo-N-[4-(11-dioxo-1lambda62-thiazolidin-2-yl)phenyl]benzene-1-sulfonamide

SMILES

O=S(c(cc1)ccc1Br)(Nc(cc1)ccc1N(CCC1)S1(=O)=O)=O

InChI

InChI=1S/C15H15BrN2O4S2/c16-12-2-8-15(9-3-12)24(21,22)17-13-4-6-14(7-5-13)18-10-1-11-23(18,19)20/h2-9,17H,1,10-11H2

InChI Key

YPFDPDDWYXPCPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08003900

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.33

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.772

Distribution Coefficient, logD

2.629

Water Solubility, LogSw

-3.31

Polar Surface Area

72.924

Acid Dissociation Constant (pKa)

7.81

Base Dissociation Constant (pKb)

-7.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G497-0019 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G497-0019 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G497-0019?
Check Price and Availability of G497-0019, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G497-0019 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G497-0019
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G497-0019
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G497-0019 available by request