G500-0837 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}cyclopropanecarboxamide

G500-0837 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}cyclopropanecarboxamide
G500-0837 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G500-0837
N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G500-0837

Molecular Formula

C23H29N3O (C23 H29 N3 O)

Compound Name

N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}cyclopropanecarboxamide

IUPAC name

N-{2-[4-(dimethylamino)phenyl]-2-(1234-tetrahydroisoquinolin-2-yl)ethyl}cyclopropanecarboxamide

SMILES

CN(C)c1ccc(C(CNC(C2CC2)=O)N(CC2)Cc3c2cccc3)cc1

InChI

InChI=1S/C23H29N3O/c1-25(2)21-11-9-18(10-12-21)22(15-24-23(27)19-7-8-19)26-14-13-17-5-3-4-6-20(17)16-26/h3-6,9-12,19,22H,7-8,13-16H2,1-2H3,(H,24,27)/t22-/m0/s1

InChI Key

ZPCMXGZVJYXJFV-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD08005570

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.918

Distribution Coefficient, logD

3.864

Water Solubility, LogSw

-3.91

Polar Surface Area

30.631

Acid Dissociation Constant (pKa)

13.26

Base Dissociation Constant (pKb)

6.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

G500-0837 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G500-0837 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G500-0837?
Check Price and Availability of G500-0837, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G500-0837 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G500-0837
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G500-0837
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G500-0837 available by request