G500-0867 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}thiophene-2-carboxamide

G500-0867 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}thiophene-2-carboxamide
G500-0867 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G500-0867
N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G500-0867

Molecular Formula

C24H27N3OS (C24 H27 N3 OS)

Compound Name

N-{2-[4-(dimethylamino)phenyl]-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl}thiophene-2-carboxamide

IUPAC name

N-{2-[4-(dimethylamino)phenyl]-2-(1234-tetrahydroisoquinolin-2-yl)ethyl}thiophene-2-carboxamide

SMILES

CN(C)c1ccc(C(CNC(c2cccs2)=O)N(CC2)Cc3c2cccc3)cc1

InChI

InChI=1S/C24H27N3OS/c1-26(2)21-11-9-19(10-12-21)22(16-25-24(28)23-8-5-15-29-23)27-14-13-18-6-3-4-7-20(18)17-27/h3-12,15,22H,13-14,16-17H2,1-2H3,(H,25,28)/t22-/m0/s1

InChI Key

XDNWYGQOOHIFDR-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD08005587

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.56

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.394

Distribution Coefficient, logD

4.378

Water Solubility, LogSw

-4.12

Polar Surface Area

31.126

Acid Dissociation Constant (pKa)

12.65

Base Dissociation Constant (pKb)

5.99

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.20

G500-0867 in Drug Discovery

Included in Screening Libraries

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G500-0867 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G500-0867?
Check Price and Availability of G500-0867, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G500-0867 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G500-0867
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G500-0867
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G500-0867 available by request