G505-0461 Screening compound: N-[1-(ETHANESULFONYL)-1,2,3,4-TETRAHYDROQUINOLIN-6-YL]-1-(2-FLUOROPHENYL)METHANESULFONAMIDE

G505-0461 Screening compound: N-[1-(ETHANESULFONYL)-1,2,3,4-TETRAHYDROQUINOLIN-6-YL]-1-(2-FLUOROPHENYL)METHANESULFONAMIDE
G505-0461 Screening compound: N-[1-(ETHANESULFONYL)-1,2,3,4-TETRAHYDROQUINOLIN-6-YL]-1-(2-FLUOROPHENYL)METHANESULFONAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G505-0461
N-[1-(ETHANESULFONYL)-1,2,3,4-TETRAHYDROQUINOLIN-6-YL]-1-(2-FLUOROPHENYL)METHANESULFONAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G505-0461

Molecular Formula

C18H21FN2O4S2 (C18 H21 FN2 O4 S2)

Compound Name

N-[1-(ETHANESULFONYL)-1,2,3,4-TETRAHYDROQUINOLIN-6-YL]-1-(2-FLUOROPHENYL)METHANESULFONAMIDE

IUPAC name

N-[1-(ethanesulfonyl)-1234-tetrahydroquinolin-6-yl]-1-(2-fluorophenyl)methanesulfonamide

SMILES

CCS(N(CCC1)c(cc2)c1cc2NS(Cc(cccc1)c1F)(=O)=O)(=O)=O

InChI

InChI=1S/C18H21FN2O4S2/c1-2-27(24,25)21-11-5-7-14-12-16(9-10-18(14)21)20-26(22,23)13-15-6-3-4-8-17(15)19/h3-4,6,8-10,12,20H,2,5,7,11,13H2,1H3

InChI Key

KYVAKFJLIRRRHU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09236217

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.750

Distribution Coefficient, logD

2.701

Water Solubility, LogSw

-3.37

Polar Surface Area

73.833

Acid Dissociation Constant (pKa)

8.32

Base Dissociation Constant (pKb)

-5.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G505-0461 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G505-0461 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G505-0461?
Check Price and Availability of G505-0461, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G505-0461 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G505-0461
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G505-0461
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G505-0461 available by request