G516-0013 Screening compound: N-(3-chloro-4-fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

G516-0013 Screening compound: N-(3-chloro-4-fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-amine
G516-0013 Screening compound: N-(3-chloro-4-fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G516-0013
N-(3-chloro-4-fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G516-0013

Molecular Formula

C21H15ClFN3O (C21 H15 ClFN3 O)

Compound Name

N-(3-chloro-4-fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

IUPAC name

N-(3-chloro-4-fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

SMILES

COc(cc1)ccc1-c1nc2ccccc2c(Nc(cc2)cc(Cl)c2F)n1

InChI

InChI=1S/C21H15ClFN3O/c1-27-15-9-6-13(7-10-15)20-25-19-5-3-2-4-16(19)21(26-20)24-14-8-11-18(23)17(22)12-14/h2-12H,1H3,(H,24,25,26)

InChI Key

HWMGCIQANGIWEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15014978

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.82

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.733

Distribution Coefficient, logD

6.696

Water Solubility, LogSw

-6.69

Polar Surface Area

35.349

Acid Dissociation Constant (pKa)

15.61

Base Dissociation Constant (pKb)

6.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

G516-0013 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Targeted Diversity Library (40567 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G516-0013 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G516-0013?
Check Price and Availability of G516-0013, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G516-0013 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G516-0013
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G516-0013
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G516-0013 available by request