G516-0380 Screening compound: N-(3-chloro-2-methylphenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

G516-0380 Screening compound: N-(3-chloro-2-methylphenyl)-2-(4-methoxyphenyl)quinazolin-4-amine
G516-0380 Screening compound: N-(3-chloro-2-methylphenyl)-2-(4-methoxyphenyl)quinazolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G516-0380
N-(3-chloro-2-methylphenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G516-0380

Molecular Formula

C22H18ClN3O (C22 H18 ClN3 O)

Compound Name

N-(3-chloro-2-methylphenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

IUPAC name

N-(3-chloro-2-methylphenyl)-2-(4-methoxyphenyl)quinazolin-4-amine

SMILES

Cc(c(Nc1nc(-c(cc2)ccc2OC)nc2ccccc12)ccc1)c1Cl

InChI

InChI=1S/C22H18ClN3O/c1-14-18(23)7-5-9-19(14)24-22-17-6-3-4-8-20(17)25-21(26-22)15-10-12-16(27-2)13-11-15/h3-13H,1-2H3,(H,24,25,26)

InChI Key

KQJBFCMFOJXGRI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02961476

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.86

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.127

Distribution Coefficient, logD

7.090

Water Solubility, LogSw

-6.75

Polar Surface Area

34.651

Acid Dissociation Constant (pKa)

17.17

Base Dissociation Constant (pKb)

6.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

G516-0380 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G516-0380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G516-0380?
Check Price and Availability of G516-0380, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G516-0380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G516-0380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G516-0380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G516-0380 available by request