G516-1255 Screening compound: 4-(4-benzylpiperidin-1-yl)-2-(4-chlorophenyl)quinazoline

G516-1255 Screening compound: 4-(4-benzylpiperidin-1-yl)-2-(4-chlorophenyl)quinazoline
G516-1255 Screening compound: 4-(4-benzylpiperidin-1-yl)-2-(4-chlorophenyl)quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G516-1255
4-(4-benzylpiperidin-1-yl)-2-(4-chlorophenyl)quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G516-1255

Molecular Formula

C26H24ClN3 (C26 H24 ClN3)

Compound Name

4-(4-benzylpiperidin-1-yl)-2-(4-chlorophenyl)quinazoline

IUPAC name

4-(4-benzylpiperidin-1-yl)-2-(4-chlorophenyl)quinazoline

SMILES

Clc(cc1)ccc1-c1nc2ccccc2c(N2CCC(Cc3ccccc3)CC2)n1

InChI

InChI=1S/C26H24ClN3/c27-22-12-10-21(11-13-22)25-28-24-9-5-4-8-23(24)26(29-25)30-16-14-20(15-17-30)18-19-6-2-1-3-7-19/h1-13,20H,14-18H2

InChI Key

PFQWEWWJKLTHIR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01856485

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.95

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

8.198

Distribution Coefficient, logD

7.613

Water Solubility, LogSw

-7.04

Polar Surface Area

21.367

Acid Dissociation Constant (pKa)

21.72

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

G516-1255 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G516-1255 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G516-1255?
Check Price and Availability of G516-1255, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G516-1255 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G516-1255
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G516-1255
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G516-1255 available by request