G516-1278 Screening compound: 2-(4-chlorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]quinazoline

G516-1278 Screening compound: 2-(4-chlorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]quinazoline
G516-1278 Screening compound: 2-(4-chlorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G516-1278
2-(4-chlorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G516-1278

Molecular Formula

C23H20ClN5 (C23 H20 ClN5)

Compound Name

2-(4-chlorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]quinazoline

IUPAC name

2-(4-chlorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]quinazoline

SMILES

Clc(cc1)ccc1-c1nc2ccccc2c(N(CC2)CCN2c2ncccc2)n1

InChI

InChI=1S/C23H20ClN5/c24-18-10-8-17(9-11-18)22-26-20-6-2-1-5-19(20)23(27-22)29-15-13-28(14-16-29)21-7-3-4-12-25-21/h1-12H,13-16H2

InChI Key

SBHYHQHWJJUVDK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15015120

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.9

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.530

Distribution Coefficient, logD

5.945

Water Solubility, LogSw

-6.88

Polar Surface Area

33.410

Acid Dissociation Constant (pKa)

22.37

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G516-1278 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G516-1278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G516-1278?
Check Price and Availability of G516-1278, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G516-1278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G516-1278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G516-1278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G516-1278 available by request