G516-1358 Screening compound: 2-(4-chlorophenyl)-4-[4-(furan-2-carbonyl)piperazin-1-yl]quinazoline

G516-1358 Screening compound: 2-(4-chlorophenyl)-4-[4-(furan-2-carbonyl)piperazin-1-yl]quinazoline
G516-1358 Screening compound: 2-(4-chlorophenyl)-4-[4-(furan-2-carbonyl)piperazin-1-yl]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G516-1358
2-(4-chlorophenyl)-4-[4-(furan-2-carbonyl)piperazin-1-yl]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G516-1358

Molecular Formula

C23H19ClN4O2 (C23 H19 ClN4 O2)

Compound Name

2-(4-chlorophenyl)-4-[4-(furan-2-carbonyl)piperazin-1-yl]quinazoline

IUPAC name

2-(4-chlorophenyl)-4-[4-(furan-2-carbonyl)piperazin-1-yl]quinazoline

SMILES

O=C(c1ccco1)N(CC1)CCN1c1nc(-c(cc2)ccc2Cl)nc2ccccc12

InChI

InChI=1S/C23H19ClN4O2/c24-17-9-7-16(8-10-17)21-25-19-5-2-1-4-18(19)22(26-21)27-11-13-28(14-12-27)23(29)20-6-3-15-30-20/h1-10,15H,11-14H2

InChI Key

GSBKKFFQUQXXDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15015134

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.435

Distribution Coefficient, logD

4.851

Water Solubility, LogSw

-6.21

Polar Surface Area

46.673

Acid Dissociation Constant (pKa)

22.60

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G516-1358 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D

References: we are preparing a list of scientific research reports with G516-1358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G516-1358?
Check Price and Availability of G516-1358, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G516-1358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G516-1358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G516-1358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G516-1358 available by request