G519-0061 Screening compound: 8-methyl-6-phenyl-N-(2-pyridylmethyl)-5,6-dihydro-4H-thieno[2,3-e]indazole-2-carboxamide

G519-0061 Screening compound: 8-methyl-6-phenyl-N-(2-pyridylmethyl)-5,6-dihydro-4H-thieno[2,3-e]indazole-2-carboxamide
G519-0061 Screening compound: 8-methyl-6-phenyl-N-(2-pyridylmethyl)-5,6-dihydro-4H-thieno[2,3-e]indazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G519-0061
8-methyl-6-phenyl-N-(2-pyridylmethyl)-5,6-dihydro-4H-thieno[2,3-e]indazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G519-0061

Molecular Formula

C23H20N4OS (C23 H20 N4 OS)

Compound Name

8-methyl-6-phenyl-N-(2-pyridylmethyl)-5,6-dihydro-4H-thieno[2,3-e]indazole-2-carboxamide

IUPAC name

8-methyl-6-phenyl-N-[(pyridin-2-yl)methyl]-4H5H6H-thieno[23-e]indazole-2-carboxamide

SMILES

Cc(c-1c2CCc3c1sc(C(NCc1ncccc1)=O)c3)nn2-c1ccccc1

InChI

InChI=1S/C23H20N4OS/c1-15-21-19(27(26-15)18-8-3-2-4-9-18)11-10-16-13-20(29-22(16)21)23(28)25-14-17-7-5-6-12-24-17/h2-9,12-13H,10-11,14H2,1H3,(H,25,28)

InChI Key

CHDOQZPVOWEHDV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142387

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.661

Distribution Coefficient, logD

3.661

Water Solubility, LogSw

-4.19

Polar Surface Area

49.265

Acid Dissociation Constant (pKa)

13.16

Base Dissociation Constant (pKb)

3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.39

G519-0061 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G519-0061 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G519-0061?
Check Price and Availability of G519-0061, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G519-0061 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G519-0061
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G519-0061
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G519-0061 available by request