G519-0095 Screening compound: 8-methyl-6-phenyl-N-[2-(pyrrolidin-1-yl)ethyl]-4H,5H,6H-thieno[2,3-e]indazole-2-carboxamide

G519-0095 Screening compound: 8-methyl-6-phenyl-N-[2-(pyrrolidin-1-yl)ethyl]-4H,5H,6H-thieno[2,3-e]indazole-2-carboxamide
G519-0095 Screening compound: 8-methyl-6-phenyl-N-[2-(pyrrolidin-1-yl)ethyl]-4H,5H,6H-thieno[2,3-e]indazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G519-0095
8-methyl-6-phenyl-N-[2-(pyrrolidin-1-yl)ethyl]-4H,5H,6H-thieno[2,3-e]indazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G519-0095

Molecular Formula

C23H26N4OS (C23 H26 N4 OS)

Compound Name

8-methyl-6-phenyl-N-[2-(pyrrolidin-1-yl)ethyl]-4H,5H,6H-thieno[2,3-e]indazole-2-carboxamide

IUPAC name

8-methyl-6-phenyl-N-[2-(pyrrolidin-1-yl)ethyl]-4H5H6H-thieno[23-e]indazole-2-carboxamide

SMILES

Cc(c-1c2CCc3c1sc(C(NCCN1CCCC1)=O)c3)nn2-c1ccccc1

InChI

InChI=1S/C23H26N4OS/c1-16-21-19(27(25-16)18-7-3-2-4-8-18)10-9-17-15-20(29-22(17)21)23(28)24-11-14-26-12-5-6-13-26/h2-4,7-8,15H,5-6,9-14H2,1H3,(H,24,28)

InChI Key

WHCZJDWKGZMJSY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15015274

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.386

Distribution Coefficient, logD

1.673

Water Solubility, LogSw

-3.89

Polar Surface Area

43.912

Acid Dissociation Constant (pKa)

14.14

Base Dissociation Constant (pKb)

9.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G519-0095 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G519-0095 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G519-0095?
Check Price and Availability of G519-0095, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G519-0095 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G519-0095
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G519-0095
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G519-0095 available by request