G533-1050 Screening compound: 1-(4-chlorophenyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

G533-1050 Screening compound: 1-(4-chlorophenyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one
G533-1050 Screening compound: 1-(4-chlorophenyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G533-1050
1-(4-chlorophenyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G533-1050

Molecular Formula

C20H21ClN4O2 (C20 H21 ClN4 O2)

Compound Name

1-(4-chlorophenyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

IUPAC name

1-(4-chlorophenyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

SMILES

O=C(C(CCN1c(cc2)ccc2Cl)C1=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C20H21ClN4O2/c21-15-4-6-16(7-5-15)25-10-8-17(20(25)27)19(26)24-13-11-23(12-14-24)18-3-1-2-9-22-18/h1-7,9,17H,8,10-14H2

InChI Key

ZILBBQJFNMCGIJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15016609

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.845

Distribution Coefficient, logD

1.025

Water Solubility, LogSw

-3.23

Polar Surface Area

45.197

Acid Dissociation Constant (pKa)

5.59

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.00

G533-1050 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G533-1050 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G533-1050?
Check Price and Availability of G533-1050, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G533-1050 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G533-1050
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G533-1050
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G533-1050 available by request