G533-1365 Screening compound: 3-(2,3-dihydro-1H-indole-1-carbonyl)-1-(4-fluorophenyl)pyrrolidin-2-one

G533-1365 Screening compound: 3-(2,3-dihydro-1H-indole-1-carbonyl)-1-(4-fluorophenyl)pyrrolidin-2-one
G533-1365 Screening compound: 3-(2,3-dihydro-1H-indole-1-carbonyl)-1-(4-fluorophenyl)pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G533-1365
3-(2,3-dihydro-1H-indole-1-carbonyl)-1-(4-fluorophenyl)pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G533-1365

Molecular Formula

C19H17FN2O2 (C19 H17 FN2 O2)

Compound Name

3-(2,3-dihydro-1H-indole-1-carbonyl)-1-(4-fluorophenyl)pyrrolidin-2-one

IUPAC name

3-(23-dihydro-1H-indole-1-carbonyl)-1-(4-fluorophenyl)pyrrolidin-2-one

SMILES

O=C(C(CCN1c(cc2)ccc2F)C1=O)N(CC1)c2c1cccc2

InChI

InChI=1S/C19H17FN2O2/c20-14-5-7-15(8-6-14)21-12-10-16(18(21)23)19(24)22-11-9-13-3-1-2-4-17(13)22/h1-8,16H,9-12H2/t16-/m0/s1

InChI Key

WCRFUCZGOKKMHZ-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15016642

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

324.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.762

Distribution Coefficient, logD

-0.892

Water Solubility, LogSw

-2.98

Polar Surface Area

32.456

Acid Dissociation Constant (pKa)

3.75

Base Dissociation Constant (pKb)

-1.41

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

G533-1365 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G533-1365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G533-1365?
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What is the minimum amount of G533-1365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G533-1365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G533-1365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G533-1365 available by request