G546-0487 Screening compound: N-(4-methoxyphenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

G546-0487 Screening compound: N-(4-methoxyphenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide
G546-0487 Screening compound: N-(4-methoxyphenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G546-0487
N-(4-methoxyphenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G546-0487

Molecular Formula

C22H17N3O2 (C22 H17 N3 O2)

Compound Name

N-(4-methoxyphenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

IUPAC name

N-(4-methoxyphenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

SMILES

COc(cc1)ccc1NC(c1cc(-c2ncccc2)nc2ccccc12)=O

InChI

InChI=1S/C22H17N3O2/c1-27-16-11-9-15(10-12-16)24-22(26)18-14-21(20-8-4-5-13-23-20)25-19-7-3-2-6-17(18)19/h2-14H,1H3,(H,24,26)

InChI Key

NMNIHSMWPRIOBQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06644054

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.278

Distribution Coefficient, logD

4.278

Water Solubility, LogSw

-4.39

Polar Surface Area

47.980

Acid Dissociation Constant (pKa)

12.50

Base Dissociation Constant (pKb)

3.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.50

G546-0487 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G546-0487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G546-0487?
Check Price and Availability of G546-0487, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G546-0487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G546-0487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G546-0487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G546-0487 available by request