G546-0493 Screening compound: N-(2-chlorophenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

G546-0493 Screening compound: N-(2-chlorophenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide
G546-0493 Screening compound: N-(2-chlorophenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G546-0493
N-(2-chlorophenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G546-0493

Molecular Formula

C21H14ClN3O (C21 H14 ClN3 O)

Compound Name

N-(2-chlorophenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

IUPAC name

N-(2-chlorophenyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

SMILES

O=C(c1cc(-c2ncccc2)nc2ccccc12)Nc(cccc1)c1Cl

InChI

InChI=1S/C21H14ClN3O/c22-16-8-2-4-10-18(16)25-21(26)15-13-20(19-11-5-6-12-23-19)24-17-9-3-1-7-14(15)17/h1-13H,(H,25,26)

InChI Key

DBILJPIYOINHPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12216301

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

359.81

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.545

Distribution Coefficient, logD

4.545

Water Solubility, LogSw

-4.64

Polar Surface Area

39.739

Acid Dissociation Constant (pKa)

10.94

Base Dissociation Constant (pKb)

3.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

G546-0493 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G546-0493 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G546-0493?
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What is the minimum amount of G546-0493 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G546-0493
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G546-0493
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G546-0493 available by request