G547-0105 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-(pyridin-3-yl)quinoline-4-carboxamide

G547-0105 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
G547-0105 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-(pyridin-3-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G547-0105
N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-(pyridin-3-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G547-0105

Molecular Formula

C28H27FN4O (C28 H27 FN4 O)

Compound Name

N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-(pyridin-3-yl)quinoline-4-carboxamide

IUPAC name

N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-2-(pyridin-3-yl)quinoline-4-carboxamide

SMILES

O=C(c1cc(-c2cnccc2)nc2ccccc12)NCC1CCN(Cc(cccc2)c2F)CC1

InChI

InChI=1S/C28H27FN4O/c29-25-9-3-1-6-22(25)19-33-14-11-20(12-15-33)17-31-28(34)24-16-27(21-7-5-13-30-18-21)32-26-10-4-2-8-23(24)26/h1-10,13,16,18,20H,11-12,14-15,17,19H2,(H,31,34)

InChI Key

QWRFJBRCXXVORE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27143888

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.957

Distribution Coefficient, logD

3.168

Water Solubility, LogSw

-4.95

Polar Surface Area

45.961

Acid Dissociation Constant (pKa)

14.99

Base Dissociation Constant (pKb)

9.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G547-0105 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

CNS Targets (44014 compounds)

MCL1 Targeted Library (12200 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G547-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G547-0105?
Check Price and Availability of G547-0105, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G547-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G547-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G547-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G547-0105 available by request