G557-0049 Screening compound: 3-methyl-2-(thiophene-2-sulfonamido)-N-[2-(trifluoromethyl)phenyl]butanamide

G557-0049 Screening compound: 3-methyl-2-(thiophene-2-sulfonamido)-N-[2-(trifluoromethyl)phenyl]butanamide
G557-0049 Screening compound: 3-methyl-2-(thiophene-2-sulfonamido)-N-[2-(trifluoromethyl)phenyl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G557-0049
3-methyl-2-(thiophene-2-sulfonamido)-N-[2-(trifluoromethyl)phenyl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G557-0049

Molecular Formula

C16H17F3N2O3S2 (C16 H17 F3 N2 O3 S2)

Compound Name

3-methyl-2-(thiophene-2-sulfonamido)-N-[2-(trifluoromethyl)phenyl]butanamide

IUPAC name

3-methyl-2-(thiophene-2-sulfonamido)-N-[2-(trifluoromethyl)phenyl]butanamide

SMILES

CC(C)C(C(Nc1c(C(F)(F)F)cccc1)=O)NS(c1cccs1)(=O)=O

InChI

InChI=1S/C16H17F3N2O3S2/c1-10(2)14(21-26(23,24)13-8-5-9-25-13)15(22)20-12-7-4-3-6-11(12)16(17,18)19/h3-10,14,21H,1-2H3,(H,20,22)/t14-/m0/s1

InChI Key

VAJDASLMDCRYDW-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD15019767

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.638

Distribution Coefficient, logD

3.637

Water Solubility, LogSw

-3.94

Polar Surface Area

65.246

Acid Dissociation Constant (pKa)

10.44

Base Dissociation Constant (pKb)

-1.62

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.30

G557-0049 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G557-0049 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G557-0049?
Check Price and Availability of G557-0049, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G557-0049 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G557-0049
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G557-0049
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G557-0049 available by request