G566-0473 Screening compound: N-{5-[({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl)sulfanyl]-1,3,4-thiadiazol-2-yl}-2,2-diphenylacetamide

G566-0473 Screening compound: N-{5-[({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl)sulfanyl]-1,3,4-thiadiazol-2-yl}-2,2-diphenylacetamide
G566-0473 Screening compound: N-{5-[({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl)sulfanyl]-1,3,4-thiadiazol-2-yl}-2,2-diphenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G566-0473
N-{5-[({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl)sulfanyl]-1,3,4-thiadiazol-2-yl}-2,2-diphenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G566-0473

Molecular Formula

C24H19N5O3S2 (C24 H19 N5 O3 S2)

Compound Name

N-{5-[({2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl)sulfanyl]-1,3,4-thiadiazol-2-yl}-2,2-diphenylacetamide

IUPAC name

N-{5-[({2-methyl-7-oxo-7H-[12]oxazolo[23-a]pyrimidin-5-yl}methyl)sulfanyl]-134-thiadiazol-2-yl}-22-diphenylacetamide

SMILES

CC(ON12)=CC2=NC(CSc2nnc(NC(C(c3ccccc3)c3ccccc3)=O)s2)=CC1=O

InChI

InChI=1S/C24H19N5O3S2/c1-15-12-19-25-18(13-20(30)29(19)32-15)14-33-24-28-27-23(34-24)26-22(31)21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-13,21H,14H2,1H3,(H,26,27,31)

InChI Key

BPLNTZOACXGGMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27144214

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.200

Distribution Coefficient, logD

4.156

Water Solubility, LogSw

-4.32

Polar Surface Area

84.156

Acid Dissociation Constant (pKa)

8.37

Base Dissociation Constant (pKb)

-2.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

G566-0473 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G566-0473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G566-0473?
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What is the minimum amount of G566-0473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G566-0473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G566-0473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G566-0473 available by request