G569-0252 Screening compound: N-{2-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-cyanophenyl)ethanediamide

G569-0252 Screening compound: N-{2-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-cyanophenyl)ethanediamide
G569-0252 Screening compound: N-{2-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-cyanophenyl)ethanediamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G569-0252
N-{2-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-cyanophenyl)ethanediamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G569-0252

Molecular Formula

C21H17ClN4O2S (C21 H17 ClN4 O2 S)

Compound Name

N-{2-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-cyanophenyl)ethanediamide

IUPAC name

N-{2-[2-(4-chlorophenyl)-4-methyl-13-thiazol-5-yl]ethyl}-N'-(2-cyanophenyl)ethanediamide

SMILES

Cc1c(CCNC(C(Nc(cccc2)c2C#N)=O)=O)sc(-c(cc2)ccc2Cl)n1

InChI

InChI=1S/C21H17ClN4O2S/c1-13-18(29-21(25-13)14-6-8-16(22)9-7-14)10-11-24-19(27)20(28)26-17-5-3-2-4-15(17)12-23/h2-9H,10-11H2,1H3,(H,24,27)(H,26,28)

InChI Key

ARQMHHLGTHDEAA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07802905

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.91

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.910

Distribution Coefficient, logD

1.812

Water Solubility, LogSw

-4.55

Polar Surface Area

74.525

Acid Dissociation Constant (pKa)

5.31

Base Dissociation Constant (pKb)

2.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

G569-0252 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G569-0252 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G569-0252?
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What is the minimum amount of G569-0252 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G569-0252
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G569-0252
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G569-0252 available by request