G574-0135 Screening compound: 4-chloro-N-{2-[2-(2-methylphenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide

G574-0135 Screening compound: 4-chloro-N-{2-[2-(2-methylphenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide
G574-0135 Screening compound: 4-chloro-N-{2-[2-(2-methylphenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G574-0135
4-chloro-N-{2-[2-(2-methylphenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G574-0135

Molecular Formula

C20H17ClN4OS (C20 H17 ClN4 OS)

Compound Name

4-chloro-N-{2-[2-(2-methylphenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide

IUPAC name

4-chloro-N-{2-[2-(2-methylphenyl)-[124]triazolo[32-b][13]thiazol-6-yl]ethyl}benzamide

SMILES

Cc(cccc1)c1-c1nn(c(CCNC(c(cc2)ccc2Cl)=O)cs2)c2n1

InChI

InChI=1S/C20H17ClN4OS/c1-13-4-2-3-5-17(13)18-23-20-25(24-18)16(12-27-20)10-11-22-19(26)14-6-8-15(21)9-7-14/h2-9,12H,10-11H2,1H3,(H,22,26)

InChI Key

OGEIEJNOJRTSLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08009939

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.201

Distribution Coefficient, logD

4.201

Water Solubility, LogSw

-4.67

Polar Surface Area

45.698

Acid Dissociation Constant (pKa)

12.40

Base Dissociation Constant (pKb)

2.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

G574-0135 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G574-0135 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G574-0135?
Check Price and Availability of G574-0135, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G574-0135 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G574-0135
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G574-0135
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G574-0135 available by request