G574-0249 Screening compound: 2-chloro-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide

G574-0249 Screening compound: 2-chloro-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide
G574-0249 Screening compound: 2-chloro-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G574-0249
2-chloro-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G574-0249

Molecular Formula

C19H14ClFN4OS (C19 H14 ClFN4 OS)

Compound Name

2-chloro-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzamide

IUPAC name

2-chloro-N-{2-[2-(3-fluorophenyl)-[124]triazolo[32-b][13]thiazol-6-yl]ethyl}benzamide

SMILES

O=C(c(cccc1)c1Cl)NCCc1csc2nc(-c3cc(F)ccc3)nn12

InChI

InChI=1S/C19H14ClFN4OS/c20-16-7-2-1-6-15(16)18(26)22-9-8-14-11-27-19-23-17(24-25(14)19)12-4-3-5-13(21)10-12/h1-7,10-11H,8-9H2,(H,22,26)

InChI Key

LKIYZZMCULTGDG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08010084

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.397

Distribution Coefficient, logD

4.397

Water Solubility, LogSw

-4.55

Polar Surface Area

45.698

Acid Dissociation Constant (pKa)

12.40

Base Dissociation Constant (pKb)

2.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

G574-0249 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G574-0249 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G574-0249?
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What is the minimum amount of G574-0249 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G574-0249
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G574-0249
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G574-0249 available by request