G576-0578 Screening compound: 4-[2-(1-METHYL-1H-PYRROL-2-YL)-5-OXO-4H,5H,6H,7H-PYRAZOLO[1,5-A]PYRIMIDIN-4-YL]-N-[3-(4-PROPYLPIPERAZIN-1-YL)PROPYL]BUTANAMIDE

G576-0578 Screening compound: 4-[2-(1-METHYL-1H-PYRROL-2-YL)-5-OXO-4H,5H,6H,7H-PYRAZOLO[1,5-A]PYRIMIDIN-4-YL]-N-[3-(4-PROPYLPIPERAZIN-1-YL)PROPYL]BUTANAMIDE
G576-0578 Screening compound: 4-[2-(1-METHYL-1H-PYRROL-2-YL)-5-OXO-4H,5H,6H,7H-PYRAZOLO[1,5-A]PYRIMIDIN-4-YL]-N-[3-(4-PROPYLPIPERAZIN-1-YL)PROPYL]BUTANAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G576-0578
4-[2-(1-METHYL-1H-PYRROL-2-YL)-5-OXO-4H,5H,6H,7H-PYRAZOLO[1,5-A]PYRIMIDIN-4-YL]-N-[3-(4-PROPYLPIPERAZIN-1-YL)PROPYL]BUTANAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G576-0578

Molecular Formula

C25H39N7O2 (C25 H39 N7 O2)

Compound Name

4-[2-(1-METHYL-1H-PYRROL-2-YL)-5-OXO-4H,5H,6H,7H-PYRAZOLO[1,5-A]PYRIMIDIN-4-YL]-N-[3-(4-PROPYLPIPERAZIN-1-YL)PROPYL]BUTANAMIDE

IUPAC name

4-[2-(1-methyl-1H-pyrrol-2-yl)-5-oxo-4H5H6H7H-pyrazolo[15-a]pyrimidin-4-yl]-N-[3-(4-propylpiperazin-1-yl)propyl]butanamide

SMILES

CCCN1CCN(CCCNC(CCCN(c2cc(-c3cccn3C)nn2CC2)C2=O)=O)CC1

InChI

InChI=1S/C25H39N7O2/c1-3-11-29-16-18-30(19-17-29)13-6-10-26-23(33)8-5-14-31-24-20-21(22-7-4-12-28(22)2)27-32(24)15-9-25(31)34/h4,7,12,20H,3,5-6,8-11,13-19H2,1-2H3,(H,26,33)

InChI Key

FBFONPYHJHCAAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15020342

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.63

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.140

Distribution Coefficient, logD

0.175

Water Solubility, LogSw

-2.03

Polar Surface Area

62.502

Acid Dissociation Constant (pKa)

15.52

Base Dissociation Constant (pKb)

8.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

64.00

G576-0578 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with G576-0578 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G576-0578?
Check Price and Availability of G576-0578, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G576-0578 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G576-0578
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G576-0578
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G576-0578 available by request