G581-0081 Screening compound: N-(3,5-dimethoxyphenyl)-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide

G581-0081 Screening compound: N-(3,5-dimethoxyphenyl)-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide
G581-0081 Screening compound: N-(3,5-dimethoxyphenyl)-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G581-0081
N-(3,5-dimethoxyphenyl)-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G581-0081

Molecular Formula

C25H25N5O4 (C25 H25 N5 O4)

Compound Name

N-(3,5-dimethoxyphenyl)-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide

IUPAC name

N-(35-dimethoxyphenyl)-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H5H6H7H-pyrazolo[15-a]pyrimidin-4-yl]acetamide

SMILES

Cn1c(cccc2)c2c(-c2nn(CCC(N3CC(Nc4cc(OC)cc(OC)c4)=O)=O)c3c2)c1

InChI

InChI=1S/C25H25N5O4/c1-28-14-20(19-6-4-5-7-22(19)28)21-13-24-29(25(32)8-9-30(24)27-21)15-23(31)26-16-10-17(33-2)12-18(11-16)34-3/h4-7,10-14H,8-9,15H2,1-3H3,(H,26,31)

InChI Key

IIQUREQVXRQMPB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15020508

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.438

Distribution Coefficient, logD

3.438

Water Solubility, LogSw

-3.68

Polar Surface Area

68.817

Acid Dissociation Constant (pKa)

10.61

Base Dissociation Constant (pKb)

1.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

G581-0081 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G581-0081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G581-0081?
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What is the minimum amount of G581-0081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G581-0081
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G581-0081
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G581-0081 available by request