G581-0209 Screening compound: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide

G581-0209 Screening compound: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide
G581-0209 Screening compound: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G581-0209
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G581-0209

Molecular Formula

C28H28N6O3 (C28 H28 N6 O3)

Compound Name

N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]acetamide

IUPAC name

N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H5H6H7H-pyrazolo[15-a]pyrimidin-4-yl]acetamide

SMILES

Cn1c(cccc2)c2c(-c2nn(CCC(N3CC(NCCc4c[nH]c(cc5)c4cc5OC)=O)=O)c3c2)c1

InChI

InChI=1S/C28H28N6O3/c1-32-16-22(20-5-3-4-6-25(20)32)24-14-27-33(28(36)10-12-34(27)31-24)17-26(35)29-11-9-18-15-30-23-8-7-19(37-2)13-21(18)23/h3-8,13-16,30H,9-12,17H2,1-2H3,(H,29,35)

InChI Key

PPESLRFWARBHRY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15020562

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.021

Distribution Coefficient, logD

3.021

Water Solubility, LogSw

-3.26

Polar Surface Area

72.308

Acid Dissociation Constant (pKa)

14.36

Base Dissociation Constant (pKb)

1.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G581-0209 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

MCL1 Targeted Library (12200 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G581-0209 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G581-0209?
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What is the minimum amount of G581-0209 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G581-0209
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G581-0209
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G581-0209 available by request