G581-0251 Screening compound: 2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]-N-[3-(propylsulfanyl)propyl]acetamide

G581-0251 Screening compound: 2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]-N-[3-(propylsulfanyl)propyl]acetamide
G581-0251 Screening compound: 2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]-N-[3-(propylsulfanyl)propyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G581-0251
2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]-N-[3-(propylsulfanyl)propyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G581-0251

Molecular Formula

C23H29N5O2S (C23 H29 N5 O2 S)

Compound Name

2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl]-N-[3-(propylsulfanyl)propyl]acetamide

IUPAC name

2-[2-(1-methyl-1H-indol-3-yl)-5-oxo-4H5H6H7H-pyrazolo[15-a]pyrimidin-4-yl]-N-[3-(propylsulfanyl)propyl]acetamide

SMILES

CCCSCCCNC(CN(c1cc(-c2cn(C)c3c2cccc3)nn1CC1)C1=O)=O

InChI

InChI=1S/C23H29N5O2S/c1-3-12-31-13-6-10-24-21(29)16-27-22-14-19(25-28(22)11-9-23(27)30)18-15-26(2)20-8-5-4-7-17(18)20/h4-5,7-8,14-15H,3,6,9-13,16H2,1-2H3,(H,24,29)

InChI Key

DTTPGCFHTDWLOB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15020583

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.626

Distribution Coefficient, logD

2.626

Water Solubility, LogSw

-3.02

Polar Surface Area

55.165

Acid Dissociation Constant (pKa)

15.56

Base Dissociation Constant (pKb)

1.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

G581-0251 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

PI3K-Targeted Library (17255 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G581-0251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G581-0251?
Check Price and Availability of G581-0251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G581-0251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G581-0251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G581-0251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G581-0251 available by request