G582-1728 Screening compound: N-[(2,5-dimethylphenyl)methyl]-4-(morpholin-4-yl)quinazoline-2-carboxamide

G582-1728 Screening compound: N-[(2,5-dimethylphenyl)methyl]-4-(morpholin-4-yl)quinazoline-2-carboxamide
G582-1728 Screening compound: N-[(2,5-dimethylphenyl)methyl]-4-(morpholin-4-yl)quinazoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G582-1728
N-[(2,5-dimethylphenyl)methyl]-4-(morpholin-4-yl)quinazoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G582-1728

Molecular Formula

C22H24N4O2 (C22 H24 N4 O2)

Compound Name

N-[(2,5-dimethylphenyl)methyl]-4-(morpholin-4-yl)quinazoline-2-carboxamide

IUPAC name

N-[(25-dimethylphenyl)methyl]-4-(morpholin-4-yl)quinazoline-2-carboxamide

SMILES

Cc1cc(CNC(c2nc3ccccc3c(N3CCOCC3)n2)=O)c(C)cc1

InChI

InChI=1S/C22H24N4O2/c1-15-7-8-16(2)17(13-15)14-23-22(27)20-24-19-6-4-3-5-18(19)21(25-20)26-9-11-28-12-10-26/h3-8,13H,9-12,14H2,1-2H3,(H,23,27)

InChI Key

NVBRKJUZNQTNHA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27144533

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.410

Distribution Coefficient, logD

4.410

Water Solubility, LogSw

-4.25

Polar Surface Area

54.232

Acid Dissociation Constant (pKa)

12.37

Base Dissociation Constant (pKb)

1.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

G582-1728 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G582-1728 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G582-1728?
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What is the minimum amount of G582-1728 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G582-1728
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G582-1728
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G582-1728 available by request