G583-1918 Screening compound: ethyl 4-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidine-6-carboxylate

G583-1918 Screening compound: ethyl 4-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidine-6-carboxylate
G583-1918 Screening compound: ethyl 4-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidine-6-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G583-1918
ethyl 4-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidine-6-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G583-1918

Molecular Formula

C24H23FN4O5 (C24 H23 FN4 O5)

Compound Name

ethyl 4-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidine-6-carboxylate

IUPAC name

ethyl 4-{[2-(34-dimethoxyphenyl)ethyl]amino}-3-(4-fluorophenyl)-[12]oxazolo[54-d]pyrimidine-6-carboxylate

SMILES

CCOC(c1nc(NCCc(cc2)cc(OC)c2OC)c(c(-c(cc2)ccc2F)no2)c2n1)=O

InChI

InChI=1S/C24H23FN4O5/c1-4-33-24(30)22-27-21(26-12-11-14-5-10-17(31-2)18(13-14)32-3)19-20(29-34-23(19)28-22)15-6-8-16(25)9-7-15/h5-10,13H,4,11-12H2,1-3H3,(H,26,27,28)

InChI Key

OCIAPZPRDGOQMI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27144963

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.958

Distribution Coefficient, logD

3.958

Water Solubility, LogSw

-4.33

Polar Surface Area

87.641

Acid Dissociation Constant (pKa)

17.28

Base Dissociation Constant (pKb)

-1.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G583-1918 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with G583-1918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G583-1918?
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What is the minimum amount of G583-1918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G583-1918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G583-1918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G583-1918 available by request