G585-1449 Screening compound: 1-[(1-ethyl-1H-indol-5-yl)sulfonyl]-N-{[4-(propan-2-yloxy)phenyl]methyl}piperidine-3-carboxamide

G585-1449 Screening compound: 1-[(1-ethyl-1H-indol-5-yl)sulfonyl]-N-{[4-(propan-2-yloxy)phenyl]methyl}piperidine-3-carboxamide
G585-1449 Screening compound: 1-[(1-ethyl-1H-indol-5-yl)sulfonyl]-N-{[4-(propan-2-yloxy)phenyl]methyl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G585-1449
1-[(1-ethyl-1H-indol-5-yl)sulfonyl]-N-{[4-(propan-2-yloxy)phenyl]methyl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G585-1449

Molecular Formula

C26H33N3O4S (C26 H33 N3 O4 S)

Compound Name

1-[(1-ethyl-1H-indol-5-yl)sulfonyl]-N-{[4-(propan-2-yloxy)phenyl]methyl}piperidine-3-carboxamide

IUPAC name

1-[(1-ethyl-1H-indol-5-yl)sulfonyl]-N-{[4-(propan-2-yloxy)phenyl]methyl}piperidine-3-carboxamide

SMILES

CCn(cc1)c(cc2)c1cc2S(N(CCC1)CC1C(NCc(cc1)ccc1OC(C)C)=O)(=O)=O

InChI

InChI=1S/C26H33N3O4S/c1-4-28-15-13-21-16-24(11-12-25(21)28)34(31,32)29-14-5-6-22(18-29)26(30)27-17-20-7-9-23(10-8-20)33-19(2)3/h7-13,15-16,19,22H,4-6,14,17-18H2,1-3H3,(H,27,30)/t22-/m0/s1

InChI Key

FIJUMLHLSDTQMG-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD15021000

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.63

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.510

Distribution Coefficient, logD

3.510

Water Solubility, LogSw

-3.64

Polar Surface Area

64.934

Acid Dissociation Constant (pKa)

12.95

Base Dissociation Constant (pKb)

-1.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.30

G585-1449 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G585-1449 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G585-1449?
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What is the minimum amount of G585-1449 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G585-1449
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G585-1449
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G585-1449 available by request