G585-1677 Screening compound: N-[(3-ethoxy-4-methoxyphenyl)methyl]-1-[(1-methyl-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

G585-1677 Screening compound: N-[(3-ethoxy-4-methoxyphenyl)methyl]-1-[(1-methyl-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide
G585-1677 Screening compound: N-[(3-ethoxy-4-methoxyphenyl)methyl]-1-[(1-methyl-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G585-1677
N-[(3-ethoxy-4-methoxyphenyl)methyl]-1-[(1-methyl-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G585-1677

Molecular Formula

C25H31N3O5S (C25 H31 N3 O5 S)

Compound Name

N-[(3-ethoxy-4-methoxyphenyl)methyl]-1-[(1-methyl-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-[(3-ethoxy-4-methoxyphenyl)methyl]-1-[(1-methyl-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CCOc(cc(CNC(C(CCC1)CN1S(c(cc1)cc2c1n(C)cc2)(=O)=O)=O)cc1)c1OC

InChI

InChI=1S/C25H31N3O5S/c1-4-33-24-14-18(7-10-23(24)32-3)16-26-25(29)20-6-5-12-28(17-20)34(30,31)21-8-9-22-19(15-21)11-13-27(22)2/h7-11,13-15,20H,4-6,12,16-17H2,1-3H3,(H,26,29)/t20-/m0/s1

InChI Key

KUKKPMLEBIVDJJ-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD15021061

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.317

Distribution Coefficient, logD

2.317

Water Solubility, LogSw

-3.00

Polar Surface Area

73.803

Acid Dissociation Constant (pKa)

13.45

Base Dissociation Constant (pKb)

-1.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

G585-1677 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G585-1677 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G585-1677?
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What is the minimum amount of G585-1677 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G585-1677
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G585-1677
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G585-1677 available by request