G586-0398 Screening compound: 8-chloro-N-(3-fluoro-4-methylphenyl)-7-methoxythieno[2,3-b]quinoline-2-carboxamide

G586-0398 Screening compound: 8-chloro-N-(3-fluoro-4-methylphenyl)-7-methoxythieno[2,3-b]quinoline-2-carboxamide
G586-0398 Screening compound: 8-chloro-N-(3-fluoro-4-methylphenyl)-7-methoxythieno[2,3-b]quinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G586-0398
8-chloro-N-(3-fluoro-4-methylphenyl)-7-methoxythieno[2,3-b]quinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G586-0398

Molecular Formula

C20H14ClFN2O2S (C20 H14 ClFN2 O2 S)

Compound Name

8-chloro-N-(3-fluoro-4-methylphenyl)-7-methoxythieno[2,3-b]quinoline-2-carboxamide

IUPAC name

8-chloro-N-(3-fluoro-4-methylphenyl)-7-methoxythieno[23-b]quinoline-2-carboxamide

SMILES

Cc(ccc(NC(c1cc(cc(ccc(OC)c2Cl)c2n2)c2s1)=O)c1)c1F

InChI

InChI=1S/C20H14ClFN2O2S/c1-10-3-5-13(9-14(10)22)23-19(25)16-8-12-7-11-4-6-15(26-2)17(21)18(11)24-20(12)27-16/h3-9H,1-2H3,(H,23,25)

InChI Key

KVJPIDOCPNJAAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27145097

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.253

Distribution Coefficient, logD

6.250

Water Solubility, LogSw

-6.42

Polar Surface Area

41.166

Acid Dissociation Constant (pKa)

9.54

Base Dissociation Constant (pKb)

2.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G586-0398 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G586-0398 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G586-0398?
Check Price and Availability of G586-0398, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G586-0398 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G586-0398
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G586-0398
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G586-0398 available by request