G610-0237 Screening compound: N-(3-chloro-4-fluorophenyl)-2-[2-(3,4-dimethylphenyl)-3-oxo-1,4,8-triazaspiro[4.5]dec-1-en-8-yl]acetamide

G610-0237 Screening compound: N-(3-chloro-4-fluorophenyl)-2-[2-(3,4-dimethylphenyl)-3-oxo-1,4,8-triazaspiro[4.5]dec-1-en-8-yl]acetamide
G610-0237 Screening compound: N-(3-chloro-4-fluorophenyl)-2-[2-(3,4-dimethylphenyl)-3-oxo-1,4,8-triazaspiro[4.5]dec-1-en-8-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G610-0237
N-(3-chloro-4-fluorophenyl)-2-[2-(3,4-dimethylphenyl)-3-oxo-1,4,8-triazaspiro[4.5]dec-1-en-8-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G610-0237

Molecular Formula

C23H24ClFN4O2 (C23 H24 ClFN4 O2)

Compound Name

N-(3-chloro-4-fluorophenyl)-2-[2-(3,4-dimethylphenyl)-3-oxo-1,4,8-triazaspiro[4.5]dec-1-en-8-yl]acetamide

IUPAC name

N-(3-chloro-4-fluorophenyl)-2-[2-(34-dimethylphenyl)-3-oxo-148-triazaspiro[4.5]dec-1-en-8-yl]acetamide

SMILES

Cc(cc1)c(C)cc1C1=NC2(CCN(CC(Nc(cc3)cc(Cl)c3F)=O)CC2)NC1=O

InChI

InChI=1S/C23H24ClFN4O2/c1-14-3-4-16(11-15(14)2)21-22(31)28-23(27-21)7-9-29(10-8-23)13-20(30)26-17-5-6-19(25)18(24)12-17/h3-6,11-12H,7-10,13H2,1-2H3,(H,26,30)(H,28,31)

InChI Key

VXMLEKZNBWBYRG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27146271

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.92

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.622

Distribution Coefficient, logD

4.574

Water Solubility, LogSw

-4.71

Polar Surface Area

60.471

Acid Dissociation Constant (pKa)

8.90

Base Dissociation Constant (pKb)

6.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

G610-0237 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G610-0237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G610-0237?
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What is the minimum amount of G610-0237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G610-0237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G610-0237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G610-0237 available by request