G610-0370 Screening compound: 8-[(3-fluorophenyl)methyl]-3-(4-methoxyphenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one

G610-0370 Screening compound: 8-[(3-fluorophenyl)methyl]-3-(4-methoxyphenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one
G610-0370 Screening compound: 8-[(3-fluorophenyl)methyl]-3-(4-methoxyphenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G610-0370
8-[(3-fluorophenyl)methyl]-3-(4-methoxyphenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G610-0370

Molecular Formula

C21H22FN3O2 (C21 H22 FN3 O2)

Compound Name

8-[(3-fluorophenyl)methyl]-3-(4-methoxyphenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one

IUPAC name

8-[(3-fluorophenyl)methyl]-3-(4-methoxyphenyl)-148-triazaspiro[4.5]dec-3-en-2-one

SMILES

COc(cc1)ccc1C1=NC2(CCN(Cc3cccc(F)c3)CC2)NC1=O

InChI

InChI=1S/C21H22FN3O2/c1-27-18-7-5-16(6-8-18)19-20(26)24-21(23-19)9-11-25(12-10-21)14-15-3-2-4-17(22)13-15/h2-8,13H,9-12,14H2,1H3,(H,24,26)

InChI Key

YYBFCVBTHBVFCF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27146337

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.802

Distribution Coefficient, logD

1.515

Water Solubility, LogSw

-3.44

Polar Surface Area

44.866

Acid Dissociation Constant (pKa)

9.36

Base Dissociation Constant (pKb)

8.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G610-0370 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G610-0370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G610-0370?
Check Price and Availability of G610-0370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G610-0370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G610-0370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G610-0370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G610-0370 available by request