G610-0385 Screening compound: 8-[(2-chloro-6-fluorophenyl)methyl]-3-(3-chlorophenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one

G610-0385 Screening compound: 8-[(2-chloro-6-fluorophenyl)methyl]-3-(3-chlorophenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one
G610-0385 Screening compound: 8-[(2-chloro-6-fluorophenyl)methyl]-3-(3-chlorophenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G610-0385
8-[(2-chloro-6-fluorophenyl)methyl]-3-(3-chlorophenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G610-0385

Molecular Formula

C20H18Cl2FN3O (C20 H18 Cl2 FN3 O)

Compound Name

8-[(2-chloro-6-fluorophenyl)methyl]-3-(3-chlorophenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one

IUPAC name

8-[(2-chloro-6-fluorophenyl)methyl]-3-(3-chlorophenyl)-148-triazaspiro[4.5]dec-3-en-2-one

SMILES

O=C1NC2(CCN(Cc(c(F)ccc3)c3Cl)CC2)N=C1c1cc(Cl)ccc1

InChI

InChI=1S/C20H18Cl2FN3O/c21-14-4-1-3-13(11-14)18-19(27)25-20(24-18)7-9-26(10-8-20)12-15-16(22)5-2-6-17(15)23/h1-6,11H,7-10,12H2,(H,25,27)

InChI Key

DVXIJDRPUYOHNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27146347

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.29

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.137

Distribution Coefficient, logD

3.459

Water Solubility, LogSw

-4.47

Polar Surface Area

37.322

Acid Dissociation Constant (pKa)

8.42

Base Dissociation Constant (pKb)

7.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

G610-0385 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

KRAS-Targeted Library (16000 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases
  • GPCR
  • Ion Channels
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G610-0385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G610-0385?
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What is the minimum amount of G610-0385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G610-0385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G610-0385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G610-0385 available by request