G610-0435 Screening compound: 3-(3,4-dimethylphenyl)-8-[(3-methylphenyl)methyl]-1,4,8-triazaspiro[4.5]dec-3-en-2-one

G610-0435 Screening compound: 3-(3,4-dimethylphenyl)-8-[(3-methylphenyl)methyl]-1,4,8-triazaspiro[4.5]dec-3-en-2-one
G610-0435 Screening compound: 3-(3,4-dimethylphenyl)-8-[(3-methylphenyl)methyl]-1,4,8-triazaspiro[4.5]dec-3-en-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G610-0435
3-(3,4-dimethylphenyl)-8-[(3-methylphenyl)methyl]-1,4,8-triazaspiro[4.5]dec-3-en-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G610-0435

Molecular Formula

C23H27N3O (C23 H27 N3 O)

Compound Name

3-(3,4-dimethylphenyl)-8-[(3-methylphenyl)methyl]-1,4,8-triazaspiro[4.5]dec-3-en-2-one

IUPAC name

3-(34-dimethylphenyl)-8-[(3-methylphenyl)methyl]-148-triazaspiro[4.5]dec-3-en-2-one

SMILES

Cc1cccc(CN(CC2)CCC2(NC2=O)N=C2c2cc(C)c(C)cc2)c1

InChI

InChI=1S/C23H27N3O/c1-16-5-4-6-19(13-16)15-26-11-9-23(10-12-26)24-21(22(27)25-23)20-8-7-17(2)18(3)14-20/h4-8,13-14H,9-12,15H2,1-3H3,(H,25,27)

InChI Key

USXWHRMQKLQHOV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27146368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.477

Distribution Coefficient, logD

2.633

Water Solubility, LogSw

-4.18

Polar Surface Area

37.322

Acid Dissociation Constant (pKa)

10.08

Base Dissociation Constant (pKb)

9.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G610-0435 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G610-0435 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G610-0435?
Check Price and Availability of G610-0435, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G610-0435 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G610-0435
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G610-0435
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G610-0435 available by request