G611-0646 Screening compound: 1-(carbamoylmethyl)-N-(3-methoxyphenyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide

G611-0646 Screening compound: 1-(carbamoylmethyl)-N-(3-methoxyphenyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide
G611-0646 Screening compound: 1-(carbamoylmethyl)-N-(3-methoxyphenyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G611-0646
1-(carbamoylmethyl)-N-(3-methoxyphenyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G611-0646

Molecular Formula

C19H18N4O4 (C19 H18 N4 O4)

Compound Name

1-(carbamoylmethyl)-N-(3-methoxyphenyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide

IUPAC name

1-(carbamoylmethyl)-N-(3-methoxyphenyl)-7-methyl-4-oxo-14-dihydro-18-naphthyridine-3-carboxamide

SMILES

Cc(cc1)nc(N(CC(N)=O)C=C2C(Nc3cc(OC)ccc3)=O)c1C2=O

InChI

InChI=1S/C19H18N4O4/c1-11-6-7-14-17(25)15(9-23(10-16(20)24)18(14)21-11)19(26)22-12-4-3-5-13(8-12)27-2/h3-9H,10H2,1-2H3,(H2,20,24)(H,22,26)

InChI Key

DADXIOKRYPDJDO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27146378

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.38

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.112

Distribution Coefficient, logD

2.110

Water Solubility, LogSw

-3.09

Polar Surface Area

89.562

Acid Dissociation Constant (pKa)

9.76

Base Dissociation Constant (pKb)

-1.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

G611-0646 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Hsp90-Targeted Library (11355 compounds)

NOTUM (Wnt signaling) Library (3881 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G611-0646 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G611-0646?
Check Price and Availability of G611-0646, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G611-0646 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G611-0646
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G611-0646
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G611-0646 available by request