G613-0349 Screening compound: 3-(4-chlorobenzenesulfonyl)-5-(2,4-dimethylbenzoyl)-N2-(2,4-dimethylphenyl)thiophene-2,4-diamine

G613-0349 Screening compound: 3-(4-chlorobenzenesulfonyl)-5-(2,4-dimethylbenzoyl)-N2-(2,4-dimethylphenyl)thiophene-2,4-diamine
G613-0349 Screening compound: 3-(4-chlorobenzenesulfonyl)-5-(2,4-dimethylbenzoyl)-N2-(2,4-dimethylphenyl)thiophene-2,4-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound G613-0349
3-(4-chlorobenzenesulfonyl)-5-(2,4-dimethylbenzoyl)-N2-(2,4-dimethylphenyl)thiophene-2,4-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G613-0349

Molecular Formula

C27H25ClN2O3S2 (C27 H25 ClN2 O3 S2)

Compound Name

3-(4-chlorobenzenesulfonyl)-5-(2,4-dimethylbenzoyl)-N2-(2,4-dimethylphenyl)thiophene-2,4-diamine

IUPAC name

3-(4-chlorobenzenesulfonyl)-5-(24-dimethylbenzoyl)-N2-(24-dimethylphenyl)thiophene-24-diamine

SMILES

Cc(cc1)cc(C)c1C(c(sc(Nc1c(C)cc(C)cc1)c1S(c(cc2)ccc2Cl)(=O)=O)c1N)=O

InChI

InChI=1S/C27H25ClN2O3S2/c1-15-5-11-21(17(3)13-15)24(31)25-23(29)26(35(32,33)20-9-7-19(28)8-10-20)27(34-25)30-22-12-6-16(2)14-18(22)4/h5-14,30H,29H2,1-4H3

InChI Key

QOMKWWMXUDYIMZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15023250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

525.09

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.367

Distribution Coefficient, logD

7.367

Water Solubility, LogSw

-6.38

Polar Surface Area

70.601

Acid Dissociation Constant (pKa)

18.20

Base Dissociation Constant (pKb)

-5.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

G613-0349 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G613-0349 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G613-0349?
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What is the minimum amount of G613-0349 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G613-0349
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G613-0349
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G613-0349 available by request