G614-0869 Screening compound: N-benzyl-2-{[4-ethyl-3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-methylacetamide

G614-0869 Screening compound: N-benzyl-2-{[4-ethyl-3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-methylacetamide
G614-0869 Screening compound: N-benzyl-2-{[4-ethyl-3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-methylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G614-0869
N-benzyl-2-{[4-ethyl-3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-methylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G614-0869

Molecular Formula

C26H28N4O2 (C26 H28 N4 O2)

Compound Name

N-benzyl-2-{[4-ethyl-3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-methylacetamide

IUPAC name

N-benzyl-2-{[4-ethyl-3-methyl-1-(4-methylphenyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}-N-methylacetamide

SMILES

CCc1cc(OCC(N(C)Cc2ccccc2)=O)nc2c1c(C)nn2-c1ccc(C)cc1

InChI

InChI=1S/C26H28N4O2/c1-5-21-15-23(32-17-24(31)29(4)16-20-9-7-6-8-10-20)27-26-25(21)19(3)28-30(26)22-13-11-18(2)12-14-22/h6-15H,5,16-17H2,1-4H3

InChI Key

DQHNEMJAICTVNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27146756

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.371

Distribution Coefficient, logD

5.371

Water Solubility, LogSw

-5.47

Polar Surface Area

46.657

Acid Dissociation Constant (pKa)

19.52

Base Dissociation Constant (pKb)

-0.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

G614-0869 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G614-0869 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G614-0869?
Check Price and Availability of G614-0869, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G614-0869 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G614-0869
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G614-0869
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G614-0869 available by request