G614-1338 Screening compound: 2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(1-phenylethyl)acetamide

G614-1338 Screening compound: 2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(1-phenylethyl)acetamide
G614-1338 Screening compound: 2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(1-phenylethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G614-1338
2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(1-phenylethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G614-1338

Molecular Formula

C24H21F3N4O2 (C24 H21 F3 N4 O2)

Compound Name

2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(1-phenylethyl)acetamide

IUPAC name

2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}-N-(1-phenylethyl)acetamide

SMILES

CC(c1ccccc1)NC(COc1cc(C(F)(F)F)c(c(-c2ccccc2)nn2C)c2n1)=O

InChI

InChI=1S/C24H21F3N4O2/c1-15(16-9-5-3-6-10-16)28-19(32)14-33-20-13-18(24(25,26)27)21-22(17-11-7-4-8-12-17)30-31(2)23(21)29-20/h3-13,15H,14H2,1-2H3,(H,28,32)/t15-/m0/s1

InChI Key

OFEXDHUBLMOHCY-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27146782

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.601

Distribution Coefficient, logD

4.601

Water Solubility, LogSw

-4.59

Polar Surface Area

54.740

Acid Dissociation Constant (pKa)

13.21

Base Dissociation Constant (pKb)

-0.76

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.80

G614-1338 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

CNS Annotated Library (688 compounds)

Human GPCR Annotated Library (5539 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G614-1338 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G614-1338?
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What is the minimum amount of G614-1338 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G614-1338
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G614-1338
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G614-1338 available by request