G614-1370 Screening compound: N-[(2-chlorophenyl)methyl]-2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}acetamide

G614-1370 Screening compound: N-[(2-chlorophenyl)methyl]-2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}acetamide
G614-1370 Screening compound: N-[(2-chlorophenyl)methyl]-2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G614-1370
N-[(2-chlorophenyl)methyl]-2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G614-1370

Molecular Formula

C23H18ClF3N4O2 (C23 H18 ClF3 N4 O2)

Compound Name

N-[(2-chlorophenyl)methyl]-2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}acetamide

IUPAC name

N-[(2-chlorophenyl)methyl]-2-{[1-methyl-3-phenyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}acetamide

SMILES

Cn(c1c2c(C(F)(F)F)cc(OCC(NCc(cccc3)c3Cl)=O)n1)nc2-c1ccccc1

InChI

InChI=1S/C23H18ClF3N4O2/c1-31-22-20(21(30-31)14-7-3-2-4-8-14)16(23(25,26)27)11-19(29-22)33-13-18(32)28-12-15-9-5-6-10-17(15)24/h2-11H,12-13H2,1H3,(H,28,32)

InChI Key

KTEMWNIHDJPZKK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27146790

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.043

Distribution Coefficient, logD

5.043

Water Solubility, LogSw

-5.09

Polar Surface Area

55.577

Acid Dissociation Constant (pKa)

13.23

Base Dissociation Constant (pKb)

-1.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G614-1370 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G614-1370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G614-1370?
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What is the minimum amount of G614-1370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G614-1370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G614-1370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G614-1370 available by request